Bioorganic and Medicinal Chemistry Letters p. 5408 - 5413 (2006)
Update date:2022-07-30
Topics:
Yeh, Vince S.C.
Kurukulasuriya, Ravi
Madar, David
Patel, Jyoti R.
Fung, Steven
Monzon, Katina
Chiou, William
Wang, Jiahong
Jacobson, Peer
Sham, Hing L.
Link
A series of structurally novel and metabolically stable bridged bicyclic carbocycle and heterocycle adamantane replacements have been synthesized and biologically evaluated. Several of these compounds exhibit excellent human and mouse 11β-HSD1 potency and
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