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Experiment details, spectral data, copies of 1H and 13C NMR spectra,
and X-ray crystallographic data. These materials are available free of
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AUTHOR INFORMATION
Corresponding Author
*pengliu@pitt.edu, *keary@scripps.edu
Notes
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The authors declare no competing financial interests.
(15) Bäckvall, J.-E.; Byström, S. E.; Nordberg, R. E. J. Org. Chem. 1984, 49,
4619–4631.
ACKNOWLEDGMENT
(16) Most of the substrates were pure
substrate-specific details, see the SI.
Z alkenes (Z:E>20:1). For
This work was financially supported by The Scripps Research Institute
(TSRI), Pfizer, Inc., the National Institutes of Health
(1R35GM125052), and the NSF (CHE-1654122). We gratefully
acknowledge the Nankai University College of Chemistry for an
International Research Scholarship (P.Y.). We thank Prof. Arnold L.
Rheingold and Dr. Curtis E. Moore (UCSD) for X-ray crystallographic
analysis, Dr. Jason S. Chen for assistance with prep-LC purification and
Mr. David E. Hill for GC-FID analysis. We appreciate Mr. Zhen Liu
and Mr. Joseph Derosa for proof reading and kind support.
(17) For clarity, throughout this manuscript E/Z notation is used to refer to the
alkene stereochemistry of the starting material prior to C(alkenyl)–H activation.
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