DESULPHURATIVE APPROACHES TO PENEM ANTIBIOTICS. IV. BROMINATION OF 3-METHYL-2-THIACEPHEMS, A NOVEL ENTRY IN THE SYNTHESIS OF POTENT ANTIMICROBIAL AGENTS

DOI: 10.1016/S0040-4039(00)88159-9

Source and publish data:

Tetrahedron Letters p. 3283 - 3286 (1983)

Update date:2022-07-29

Topics:

Authors:

Perrone, Ettore

Alpegiani, Marco

Bedeschi, Angelo

Giudici, Franco

Foglio, Maurizio

Franceschi, Giovanni

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88159-9

The 3-methyl group in 2-thiacephem-4-carboxylates can be brominated in good yield, thus providing access to a series of highly active penem antibiotics.

Full text of DOI:10.1016/S0040-4039(00)88159-9

Products guided by the article

Product name:(6R,7S)-3-Bromomethyl-7-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-8-oxo-4,5-dithia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Cas No:91685-88-0

R&D Labs maybe for 91685-88-0

Tianjin Bright Future Technology Co., Ltd

Contact:0086-22-58016666

Address:NO.136 DongTeng Lake Street Tianjin Economic and Technology Development Area,Tainjin,China
Jiaozuo Zhongwei Special Products Pharmaceutical Co.,Ltd.

website:http://www.zw-pvp.com

Contact:15302105619

Address:Jiaozuo,Henan,China (Mainland)
Zhejiang Kaili Industrial Co., Ltd

Contact:+86-571-85241926

Address:lantian business center,No.18 Moganshan Road
Shanghai Mio Chemical Co., Ltd

Contact:0086 21- 64401188-622

Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Lyrin Industrial Corporation Limited

Contact:86-731-82571800

Address:Rm 2408,Asia Economy International Building,Shaoshan Road South,Yuhua District,Changsha,Hunan,China

Relevant to this article

IDENTIFICATION OF ETHINAMATE, ETHCHLORVYNOL, AND METHYLPARAFYNOL.

Doi:10.1002/jps.2600530740
(1964)
Asymmetric Palladium-Catalyzed Oxycarbonylation of Terminal Alkenes: Efficient Access to β-Hydroxy Alkylcarboxylic Acids

Doi:10.1002/anie.202104252
(2021)
Regioselective synthesis of substituted pyrroles: Efficient palladium-catalyzed cyclization of internal alkynes and 2-amino-3-iodoacrylate derivatives

Doi:10.1021/ol062424p
(2006)
Tandem reduction-olefination for the stereoselective synthesis of (Z)-α-fluoro-α,β-unsaturated esters

Doi:10.1016/S0040-4039(03)00778-0
(2003)
C ₂-Symmetric S/C/S ligands based on N-heterocyclic carbenes: A new ligand architecture for asymmetric catalysis

Doi:10.1039/b910846g
(2009)
Improving the gelation properties of 3,5-diaminobenzoate-based organogelators in aromatic solvents with additional aromatic-containing pendants

Doi:10.1016/j.tet.2006.10.066
(2007)

Article Doi