Synthesis and enzyme-inhibitory activity of methyl acarviosin analogues having the α-manno configuration

Article abstract of DOI:10.1016/0008-6215(92)84056-X

Two methyl acarviosin analogues 3a and 4a, having the α-manno configuration, and their dihydro derivatives 6a and 7a were synthesized by coupling the protected pseudo-sugar epoxides with methyl 4-amino-4-deoxy- and -4,6-dideoxy-α-D-mannopyranoside.Similar