Synthesis of Substituted 2-Imidazolidinones and Annelated Hydantions via Aminoalkylation Transformations

Article abstract of DOI:10.1021/jo00199a001

The synthetic utility of 4-hydroxy-2-imidazolidinone amidoalkylation reactions is limited by the propensity of the carbon-5 unsubstituted and carbon-5 monosubstituted adducts to undergo dehydration to yield 2-imidazolones.Two techniques are reported which