Furan Ring Opening – Pyridine Ring Closure: An Efficient Approach towards 6H-Isochromeno[4,3-b]pyridin-6-ones from Readily Available Furans and Phthalaldehydic Acid Methyl Esters

DOI: 10.1002/ejoc.201701355

Source and publish data:

European Journal of Organic Chemistry p. 461 - 469 (2018)

Update date:2022-09-26

Topics:

Authors:

Shpuntov, Pavel M.

Kolodina, Alexandra A.

Uchuskin, Maxim G.

Abaev, Vladimir T.

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Article abstract of DOI:10.1002/ejoc.201701355

An efficient iodine-catalyzed three-component Mannich-type reaction of various 2-alkylfurans, methyl 2-formylbenzoates and carbamates under mild reaction conditions was realized. Synthetic utility of the resulting N-Boc-1-[2-(carbomethoxy)aryl]furfurylami

Full text of DOI:10.1002/ejoc.201701355

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