Sleep-Inducing N-Alkyl-5--5-hydroxy-2-pyrrolidinones and N-Alkyl-3-(trifluoromethyl)cinnamamides

DOI: 10.1021/jm00379a007

Source and publish data:

Journal of Medicinal Chemistry p. 28 - 31 (1985)

Update date:2022-08-05

Topics: Nuclear magnetic resonance (NMR) spectroscopy High-performance liquid chromatography (HPLC) Chemical Synthesis

Authors:

Houlihan, William J.

Gogerty, John H.

Ryan, Eileen A.

Schmitt, Gemma

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Article abstract of DOI:10.1021/jm00379a007

A series of N-alkyl-3--5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)-cinnamamides were prepared and screened in a series of tests designed to detect potential sleep inducers.The more active members of the series wer

Full text of DOI:10.1021/jm00379a007

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