[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 3. Variation in the bridge between the aromatic rings to complete mapping of the receptor

DOI: 10.1021/jm00379a016

Source and publish data:

Journal of Medicinal Chemistry p. 79 - 93 (1985)

Update date:2022-08-04

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Authors:

Plattner

Martin Martin

Smital Smital

et al. et al.

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Article abstract of DOI:10.1021/jm00379a016

Continued structural evaluation of the [(aminomethyl)aryloxy]acetic ester diuretics has produced a series of compounds in which the functional group that bridges the two aromatic rings has been varied. Diuretic screening of these analogues in rats indicat

Full text of DOI:10.1021/jm00379a016

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Product name:Acetic acid, [4-[[3-(aminomethyl)-4-hydroxyphenoxy]methyl]-2,3-dichlorophenoxy]-, ethyl ester, hydrochloride

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