Journal of Medicinal Chemistry p. 111 - 116 (1985)
Update date:2022-08-02
Topics:
Gray
Platz
Chang
Leverone
Ferrick
Kramer
A number of compounds were synthesized and tested for their ability to realkylate the phosphonate anion of 'aged', soman-inhibited acetylcholinesterase. None were found able to do so, but two of the compounds in particular, [2-(4-pyridyl)ethyl]diethylmethylammonium iodide and its 2-isomer, proved able to slow the rate of aging significantly.
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