European Journal of Medicinal Chemistry p. 109 - 113 (2007)
Update date:2022-07-29
Topics:
Springer, Dane M.
Bunker, Amy
Luh, Bing-Yu
Sorenson, Margaret E.
Goodrich, Jason T.
Bronson, Joanne J.
DenBleyker, Kenneth
Dougherty, Thomas J.
Fung-Tomc, Joan
Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in vitro as antibacterial agents. Four of the compounds described were found to have MICs ≤ 4 μg/mL against marker strains of Strepto
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