Regio- and stereoselective synthesis of isoindolin-1-ones via electrophilic cyclization

DOI: 10.1021/jo048007c

Source and publish data:

Journal of Organic Chemistry p. 1432 - 1437 (2005)

Update date:2022-07-29

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Authors:

Yao, Tuanli

Larock, Richard C.

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Article abstract of DOI:10.1021/jo048007c

(Chemical Equation Presented) A variety of substituted isoindolin-1-ones are readily prepared in good to excellent yields under very mild reaction conditions by the reaction of o-(1-alkynyl)benzamides with ICl, I₂, and NBS. In a few cases, subs

Full text of DOI:10.1021/jo048007c

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