(-)-Ternatin, a highly N-methylated cyclic heptapeptide that inhibits fat accumulation: structure and synthesis

Article abstract of DOI:10.1016/j.tetlet.2006.04.073

A highly N-methylated cyclic heptapeptide, (-)-ternatin, was isolated from the mushroom Coriolus versicolor, which significantly suppressed fat accumulation against 3T3-L1 murine adipocytes (EC₅₀ = 0.14 μg/mL). Although ternatin was previously