SYNTHESIS OF 1-β-METHYLCARBAPENEM KEY INTERMEDIATES INVOLVING THE LABILE ACYL AUXILIARY 4,4-DIMETHYL-1,3-OXAZOLIDINE-2-THIONE

DOI: 10.1016/S0040-4039(00)99461-9

Source and publish data:

Tetrahedron Letters p. 1345 - 1348 (1989)

Update date:2022-09-26

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Authors:

Deziel, Robert

Favreau, Denis

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Article abstract of DOI:10.1016/S0040-4039(00)99461-9

A convenient synthesis of 1-β-methylcarbapenem key intermediates based on the facile displacement of the 4,4-dimethyl-1,3-oxazolidine-2-thione auxiliary of 5 is described.

Full text of DOI:10.1016/S0040-4039(00)99461-9

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