Epoxygenase eicosanoids: Synthesis of tetrahydrofuran-diol metabolites and their vasoactivity

DOI: 10.1016/j.bmcl.2007.01.096

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Bioorganic and Medicinal Chemistry Letters p. 2634 - 2638 (2007)

Update date:2022-08-03

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Authors:

Falck Falck

Manmohan Reddy

Byun, Kihwan

Campbell, William B.

Yi, Xiu-Yu

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Article abstract of DOI:10.1016/j.bmcl.2007.01.096

Eight members of a recently identified family of tetrahydrofuran-diols (THFDs), originating from epoxyeicosatrienoic acids (EETs), were prepared stereospecifically from d-(+)-glucose. The THFDs potently induced relaxation of pre-contracted bovine arteries

Full text of DOI:10.1016/j.bmcl.2007.01.096

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