Chemical and Pharmaceutical Bulletin p. 3373 - 3377 (1984)
Update date:2022-08-03
Topics:
Watanabe
Kawada
Takamoto
et al.
5-Acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one (3a, AG-629), previously found to be the most potent antiulcer compound in a series of spirocyclopropanes, was obtained by one step synthesis starting from methyl 5-acetyl-2-[(tetrahydro-2-oxo-3-furanyl)oxy]benzoate (1a). In this reaction, 5,10'-(diacetyl-5',6'-dihydrospiro[benzofuran-2(3H),4'(3'H)-[2H]oxocino[3, 2-b]-benzofuran]-3-one (5a), which has a new ring system, and 1H,3H-8-acetyl-4,5-dihydro-naphtho[1,2-c:4,3-b']difuran-1-one (6) were isolated as by-products. A possible reaction mechanism is presented.
View MoreQINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED
Contact:+86-0532-82683616
Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Wuhan Kemi-Works Chemical Co., Ltd
website:http://www.kemiworks.com
Contact:86-27-85736489
Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Daicel Chiral Technologies (China)CO.,LTD
Contact:021-5046-0086*8
Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
Sichuan WeiKeqi Biological Technology Co., Ltd.
website:https://www.weikeqi-biotech.com/en
Contact:86-028-81700200
Address:sichuan Chengdu Qingjiang Zhonglu 63号
Yantai Derun Liquid Crystal Materials Co. Ltd.
website:http://www.ytderun.com
Contact:86-535-6300169
Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI
Doi:10.1002/jps.2600520707
(1963)Doi:10.1134/S1070428006100253
(2006)Doi:10.1039/b707772f
(2007)Doi:10.1016/S0040-4020(01)91508-X
(1984)Doi:10.1016/j.tetasy.2007.06.009
(2007)Doi:10.1021/ja00294a048
(1985)
