An efficient synthesis of aryl phenaceturates using acid catalyzed dicyclohexylcarbodiimide esterification and transient N-tert-butoxycarbonylation

DOI: 10.1055/s-1994-25507

Source and publish data:

Synthesis p. 480 - 482 (1994)

Update date:2022-08-04

Topics: Esterification Acid catalyzed

Authors:

Cabaret Cabaret

Liu Liu

Wakselman

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Article abstract of DOI:10.1055/s-1994-25507

Application of the Holmberg procedure (DCC/pyridine/p-TSA(cat)) improves the yield of the direct condensation of phenols with phenylacetylglycine (1). Moreover, N-tert-butoxycarbonylation of 1 impedes an intramolecular reaction leading to an oxazolone, an

Full text of DOI:10.1055/s-1994-25507

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