An efficient synthesis of aryl phenaceturates using acid catalyzed dicyclohexylcarbodiimide esterification and transient N-tert-butoxycarbonylation

Article abstract of DOI:10.1055/s-1994-25507

Application of the Holmberg procedure (DCC/pyridine/p-TSA(cat)) improves the yield of the direct condensation of phenols with phenylacetylglycine (1). Moreover, N-tert-butoxycarbonylation of 1 impedes an intramolecular reaction leading to an oxazolone, an