A modified approach to the phomoidrides: synthesis of a late-stage intermediate containing a key carbon quaternary stereocenter

Article abstract of DOI:10.1016/j.tet.2007.02.106

A previously developed approach to the synthesis of the phomoidrides has been modified to incorporate all necessary carbon atoms prior to the key tandem carbonylation/Cope rearrangement reaction. This modification necessitated the synthesis of a challengi