Palladium-catalyzed synthesis of nucleoside adducts from bay- and fjord-region diol epoxides

DOI: 10.1021/jo070204z

Source and publish data:

Journal of Organic Chemistry p. 5035 - 5045 (2007)

Update date:2022-08-03

Topics: Column chromatography Mass spectrometry (MS) HPLC (high-performance liquid chromatography) Epoxide Reaction Kinetics Polycyclic Aromatic Hydrocarbons (PAHs) Palladium-Catalyzed Synthesis Electrophilic addition Diol DNA adducts NMR spectroscopy (Nuclear Magnetic Resonance) Enzymatic Digestion

Authors:

Champeil, Elise

Pradhan, Padmanava

Lakshman, Mahesh K.

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Article abstract of DOI:10.1021/jo070204z

(Chemical Equation Presented) Palladium-catalyzed C-N bond formation has been utilized to synthesize covalent 2′-deoxyadenosine (dA) and 2′-deoxyguanosine (dG) adducts of benzo[a]pyrene (BaP) series 1 (syn) and benzo[c]phenanthrene (BcPh) series 2 (anti)

Full text of DOI:10.1021/jo070204z

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Product name:N²-[1-(2,3,4-trisbenzoyloxy-1,2,3,4-tetrahydrobenzo[c]phenanthrenyl)]-O⁶-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine

Cas No:945548-64-1

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