SYNTHESIS OF MACROHETROCYCLES ON THE BASIS OF 2,2-DIMETHYL-4-OXOTETRAHYDROPYRAN

Article abstract of DOI:10.1007/BF00505706

Macrocyclic compounds of a new type were synthesized by the reaction of 2,2-dimethyl-4-oxo-5,5-bis(γ-succinimidooxycarbonylethyl)tetrahydropyran with diamines under conditions that do not require high dilution of the reagents.It was established that 1,9-diaza-12,15-dioxa-2,8-dioxocycloheptadecane-5-spiro-3'-(6,6-dimethyl-4-oxo)tetrahydropyran forms a complex that includes water molecules.