Heterocycles p. 1951 - 1966 (2007)
Update date:2022-07-29
Topics:
Ibrahim, Hamada Mohamed
Makhseed, Saad
Abdel-Motaleb, Ramadan Maawad
Makhlouf, Abdel-Moneim Abdel-Salam
Elnagdi, Mohamed Hilmy
Cyanoacetamides (7a-c) were prepared via reacting cyanoacetic acid (5) with amines in the presence of acetic anhydride. Compounds (7a-c) coupled with benzenediazonium chloride to yield the phenylhydrazones (8a-c). These reacted with chloroacetonitrile to yield aminopyrazolecarboxamides (11a-c). Reaction of (8a,b) with hydroxylamine hydrochloride in DMF in presence of anhydrous sodium acetate afforded the amino-1,2,3-triazolecarboxamides (36a,b). Also compounds (7a-c) reacted with dimethylformamide dimethylacetal (DMFDMA) to yield the enamines (9a-c) which react with hydrazine hydrate to afford the aminopyrazoles (16a-c). Compounds (16) and (36) reacted with DMFDMA to yield the title heterocyclic derivatives.
View MoreLaohekou Jinghong Chemical Co.,Ltd
Contact:+86-0710-3702747
Address:163.East,Huagong Road,Laohekou
Huaian Double Win Chemicals Co.,Ltd.
Contact:+86-13511538872
Address:Blk 43,Greenland Century Town,Huaian District, Huaian City,Jiangsu Province,China
Shanghai Yongyi Biotechnology Co., Ltd
Contact:+86-0512-69561955
Address:Suite 3005, City Gateway, No.398 North CaoXi Road, XuHui District, Shanghai 200030, China.
shanghai hekang chemical co.ltd
Contact:021-54173790
Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
jiangsu hualin chemical co.,ltd.
Contact:86-25-87787402
Address:jaingsu,china
Doi:10.1016/j.tet.2004.08.001
(2004)Doi:10.1007/s10847-010-9826-0
(2011)Doi:10.1016/0008-6215(88)80014-4
(1988)Doi:10.1016/j.poly.2007.04.039
(2007)Doi:10.1002/jhet.1023
(2012)Doi:10.1021/acs.joc.8b02655
(2018)