
Journal of Organic Chemistry p. 1261 - 1264 (1985)
Update date:2022-07-31
Topics:
Gonzales, Antonio G.
Ciccio, Jose F.
Rivera, A. Patricio
Martin, Julio D.
The red alga Laurencia perforata contains a variety of secondary metabolites, some of which have previously been described from other sources.We report here the isolation and structural determination of three new diterpenoids.The bicarbocyclic diterpene 1 was shown to be related with the also isolated, and previously known, isoaplysin-20 (2).The structures of the two more polar diterpenes isolated from the extract were shown to be 3,15-dibromo-7,16-dihydroxyisopimar-9(11)-ene (5) and 3,15-dibromo-7,12,16-trihydroxyisopimar-9(11)-ene (7).Extensive 1H NMR decoupling studies and some degradative experiments were used to establish the structures.
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