Selective detachment of Boc-protected amino acids and peptides from Merrifield, PAM and Wang resins by trimethyltin hydroxide

DOI: 10.1016/S0040-4020(98)00805-9

Source and publish data:

Tetrahedron p. 13023 - 13034 (1998)

Update date:2022-08-03

Topics:

Authors:

Furlan, Ricardo L. E.

Mata, Ernesto G.

Mascaretti, Oreste A.

Pena, Clara

Coba, Marcelo P.

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Article abstract of DOI:10.1016/S0040-4020(98)00805-9

We describe the development of a new non-acidolytic and non- nucleophilic method for the selective cleavage by trimethyltin hydroxide of amino acids and dipeptides at benzyl ester links attached to resins commonly used in peptide synthesis.

Full text of DOI:10.1016/S0040-4020(98)00805-9

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