BLOCKSYNTHESE VON O-GLYCOPEPTIDEN UND ANDEREN T-ANTIGEN STRUKTUREN

Article abstract of DOI:10.1016/0008-6215(84)85006-5

Under the conditions of in situ anomerisation, the 2-azido-4,6-di-O-benzoyl-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyl bromide reacted directly and with high selectivity with the reactive hydroxyl groups of L-serine and L-threonine derivatives to form α-glycosidically-linked products.Thus, the glycopeptides containing L-serine and L-threonine are more accessible.The disaccharide block could also be coupled with other reactive hydroxyl compounds to give compounds that contain the T-receptor.