Synthesis of (4R)-D,L-- and (4S)-D,L-Homoserine Lactones

Article abstract of DOI:10.1021/jo00213a012

The (4R)-D,L-<4-2H>- and (4S)-D,L-<4-2H>homoserine lactone hydrochloride salts were prepared from D,L-3-amino-3-(4-methoxyphenyl)propanoic acid (1) in eight steps in an overall yields of 5.0percent.Amino acid 1 was converted into D,L-3-<<(1,1-dimethyletho