Acetoacetylation with 2,2,6-Trimethyl-4H-1,3-dioxin-4-one: A Convenient Alternative to Diketene.

DOI: 10.1021/jo00214a006

Source and publish data:

Journal of Organic Chemistry p. 2431 - 2435 (1985)

Update date:2022-07-29

Topics:

Authors:

Clemens, Robert J.

Hyatt, John A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00214a006

The diketene/acetone adduct, 2,2,6-trimethyl-4H-1,3-dioxin-4-one, efficiently acetoacetylates aliphatic and aromatic alcohols, amines, and thiols.These acetoacetylation reactions are fast and stoichiometric, require no catalysis, and give only volatile byproducts.

Full text of DOI:10.1021/jo00214a006

Products guided by the article

Product name:3-Oxo-butyric acid (2R,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester

Cas No:96453-23-5

R&D Labs maybe for 96453-23-5

Aqua Chem Industry Co., Ltd

Contact:+86-515-88356562

Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
WEIFANG RICHEM INTERNATIONAL LTD

Contact:86-536-2222176

Address:weifang,shandong
Wuhan Soleado Technology Co.,Ltd.

Contact:86-2783341481 18971291927

Address:RM2405 Unit 1 Builing 1, Taiyin Tower, Changqing Road,Wuhan China
SHAANXI TOP PHARM CHEMICAL CO.LTD

Contact:+86-029-85733403

Address:No.108 ,west sector,south er huan,xi'an,china

Relevant to this article

Flash Vacuum Pyrolysis of Organomanganese Pentacarbonyl Compounds

Doi:10.1021/ja00304a043
(1985)
Synthesis of new (trifluoromethyl)-1H-benzo[e][1,2,4]triazolo[1,2-a][1,2,4]triazine-1,3(2H)-diones and (trifluoromethyl)benzo[5,6][1,2,4]triazino [1,2-b]phthalazine-8,13-diones

Doi:10.1016/j.jfluchem.2016.12.004
(2017)
Reactions of 1-cyanoimidazoles with phenols

Doi:10.1023/A:1012401028728
(2001)
Aromatic Nucleophilic Substitution. 21. Electronic Structures of 1,3-Dinitro-4-phenanthryl Methyl Ether and the 4,4-Disubstituted 1,3-Dinitrophenanthrene Meisenheimer Complex

Doi:10.1021/jo00225a024
(1985)
PROCYANIDIN DIMERS AND TRIMERS FROM DOUGLAS FIR INNER BARK

Doi:10.1016/S0031-9422(00)97836-1
(1989)
A second-generation formal synthesis of (+)-haplophytine

Doi:10.1002/ejoc.201001629
(2011)

Article Doi