
Journal of Medicinal Chemistry p. 1204 - 1208 (1985)
Update date:2022-08-04
Topics:
Kerekes, Peter
Sharma, Padam N.
Brossi, Arnold
Chignell, Colin F.
Quinn, Frank R.
Novel and known analogues of thiocolchicine were evaluated in a tubulin binding assay in vivo in mice for acute toxicity and in the P338 lymphocytic leukemia assay.This evaluation included N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl)deacetylthiocolch
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