Synthesis an Biological Effects of Novel Thiocolchicines. 3. Evaluation of N-Acyldeacetylthiocolchicines, N-(Alkoxycarbonyl)deacetylthiocolchicines, and O-Ethyldemethylthiocolchicines. New Synthesis of Thiodemecolcine and Antileukemic Effects of 2-Demethy

DOI: 10.1021/jm00147a014

Source and publish data:

Journal of Medicinal Chemistry p. 1204 - 1208 (1985)

Update date:2022-08-04

Topics:

Authors:

Kerekes, Peter

Sharma, Padam N.

Brossi, Arnold

Chignell, Colin F.

Quinn, Frank R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00147a014

Novel and known analogues of thiocolchicine were evaluated in a tubulin binding assay in vivo in mice for acute toxicity and in the P338 lymphocytic leukemia assay.This evaluation included N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl)deacetylthiocolch

Full text of DOI:10.1021/jm00147a014

Products guided by the article

Product name:N-(Phenoxycarbonyl)deacetylthiocolchicine

Cas No:96737-27-8

R&D Labs maybe for 96737-27-8

A.M FOOD CHEMICAL CO., LIMITED

Contact:86-531-87100375

Address:20Floor，Bblock，1Building，pharma-valley，Jinan，China
Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
Anhui Asahikasei Chemical Co., Ltd

Contact:86-551-4259770

Address:No. 88 Linquan Road Hefei Anhui China
Anhui Sunsing Chemicals Co.,Ltd

website:http://www.sunsingchem.com

Contact:0086-566-2023179

Address:Jin An industry park, Chizhou economic technical development zone, Anhui
Tomo Pharma Chem Co., Limited

Contact:+86-158-05817090

Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD

Relevant to this article

Doi:10.1021/jo00827a030
(1970)
Doi:10.1021/jo01166a020
(1947)
SYNTHESIS OF N-(INDOL-3-YL)-N',N'-DIALKYLAMIDINES BY THE VILSMEIER REACTION WITH 3-AMINOINDOLES

Doi:10.1007/BF00505902
(1985)
Synthesis of homoallylic (but-3-enylic) alcohols from aldehydes with allylic chlorides, tin(II) chloride and potassium iodide in water

Doi:10.1039/a608487g
(1997)
Highly Electron-Deficient Pyridinium-Nitrones for Rapid and Tunable Inverse-Electron-Demand Strain-Promoted Alkyne-Nitrone Cycloaddition

Doi:10.1021/acs.orglett.9b01863
(2019)
Doi:10.1021/jo01054a513
(1962)

Article Doi