Synthesis and Structure-Activity Relationships of a New Series of Antiarrhytmic Agents: 4,4-Disubstituted Hexahydro-3H-pyridopyrimidin-3-ones and Related Compounds

DOI: 10.1021/jm00147a029

Source and publish data:

Journal of Medicinal Chemistry p. 1285 - 1291 (1985)

Update date:2022-08-05

Topics:

Authors:

Chorvat, Robert J.

Prodan, Kathleen A.

Adelstein, Gilbert W.

Rydzewski, Robert M.

McLauglin, Kathleen T.

et al. et al.

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Article abstract of DOI:10.1021/jm00147a029

A series of 4,4-disubstituted tetrahydro- and 4,4-disubstituted hexahydro-3H-pyrido<1,2-c>pyrimidin-3-ones (4 and 5, respectively) were prepared from 2-aryl-2-(2-piperidinyl)-4-butanamides (2).Individual racemates of the piper

Full text of DOI:10.1021/jm00147a029

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