Preparation of Acetals of α-Epoxyketones and Their Chemoselective Hydrolysis Into α-Epoxyketones by Acidic Moist Silica Gel

DOI: 10.1055/s-1987-27964

Source and publish data:

Synthesis p. 404 - 406 (1987)

Update date:2022-08-03

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Authors:

Lescure, Pascal

Huet, Francois

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Article abstract of DOI:10.1055/s-1987-27964

Sulfur ylides react with monoacetals of α-dicarbonyl compounds to give the expected epoxyacetals in satisfactory to figh yields.These lead to α-epoxyketones by chemoselective hydrolysis by acidic moist silica gel.

Full text of DOI:10.1055/s-1987-27964

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