Chemical synthesis of 1-dephospho derivative of escherichia coli lipid A

Article abstract of DOI:10.1016/S0040-4039(00)61962-7

1-Dephospho E. coli lipid A (3) was synthesized and shown to be identical with the corresponding derivative isolated from bacterial cells. This provides the unequivocal evidence supporting the structure of E. coli lipid A (2) recently proposed by us.