Examination of a Series of 8-propyl>-1-aryl-1,3,8-triazaspirodecan-4-ones as Potential Antipsychotic Agents

DOI: 10.1021/jm00150a011

Source and publish data:

Journal of Medicinal Chemistry p. 1811 - 1817 (1985)

Update date:2022-08-03

Topics:

Authors:

Wise, Lawrence D.

Pattison, Ian C.

Butler, Donald E.

DeWald, Horace A.

Lewis, Edward P.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00150a011

8-<3-propyl>-1-phenyl-1,3,8-triazaspiro<4.5>decan-4-one (3) and related compounds have been shown to have antipsychotic profiles in biochemical and behavioral pharmacological test models.The dose of 3 necessary to produce catalep

Full text of DOI:10.1021/jm00150a011

Products guided by the article

Product name:8-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

Cas No:97861-01-3

R&D Labs maybe for 97861-01-3

Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China
YingYing Pharmaceutical Co.,Ltd

Contact:86-18854126208

Address:55#, yingxiongshan road
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone
Changzhou naidechemical Co.Ltd

Contact:+86-519-82589807

Address:NO.25,Houyang street,Jintan,Changzhou City

Relevant to this article

ANSA-STEROIDS

Doi:10.1016/S0040-4039(00)98316-3
(1985)
Physical-chemical studies and reactivity of new divalent germanium species

Doi:10.1016/s0020-1693(96)05294-2
(1996)
Synthesis of derivatives of (2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoic acid, a constituent of the didemnins

Doi:10.1039/P19960001427
(1996)
The Acrylamide Moiety as an Activated Alkene Component in the Intramolecular Baylis-Hillman Reaction: Facile Synthesis of Functionalized α-Methylene Lactam and Spirolactam Frameworks

Doi:10.1002/ejoc.201301526
(2014)
Doi:10.1021/jm00234a008
(1976)
Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

Doi:10.1016/S0040-4039(96)02083-7
(1996)

Article Doi