Examination of a Series of 8-propyl>-1-aryl-1,3,8-triazaspirodecan-4-ones as Potential Antipsychotic Agents

DOI: 10.1021/jm00150a011

Source and publish data:

Journal of Medicinal Chemistry p. 1811 - 1817 (1985)

Update date:2022-08-03

Topics:

Authors:

Wise, Lawrence D.

Pattison, Ian C.

Butler, Donald E.

DeWald, Horace A.

Lewis, Edward P.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00150a011

8-<3-propyl>-1-phenyl-1,3,8-triazaspiro<4.5>decan-4-one (3) and related compounds have been shown to have antipsychotic profiles in biochemical and behavioral pharmacological test models.The dose of 3 necessary to produce catalep

Full text of DOI:10.1021/jm00150a011

Products guided by the article

Product name:8-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

Cas No:97861-01-3

R&D Labs maybe for 97861-01-3

Jiangxi Lanqi Fine Chemical S&T Co., Ltd.

Contact:+86-21-64891143

Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
CHANGYI CITY FENGRUN FINE CHEMICAL CO.,LTD

website:http://www.fengrunhuagong.com

Contact:+86-536-7869976

Address:Changyi Coastal Economic Development Zone
Beijing Wisdom Chemicals Co., Ltd.

Contact:+86-10-52350335

Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
Jinan Hongfangde Pharmatech Co.,Ltd

Contact:86-531-88870908

Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
Alchemy industrial limited

Contact:+86-18200374913

Address:Hongmei Road, No. 99

Relevant to this article

ANSA-STEROIDS

Doi:10.1016/S0040-4039(00)98316-3
(1985)
Physical-chemical studies and reactivity of new divalent germanium species

Doi:10.1016/s0020-1693(96)05294-2
(1996)
Synthesis of derivatives of (2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoic acid, a constituent of the didemnins

Doi:10.1039/P19960001427
(1996)
The Acrylamide Moiety as an Activated Alkene Component in the Intramolecular Baylis-Hillman Reaction: Facile Synthesis of Functionalized α-Methylene Lactam and Spirolactam Frameworks

Doi:10.1002/ejoc.201301526
(2014)
Doi:10.1021/jm00234a008
(1976)
Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

Doi:10.1016/S0040-4039(96)02083-7
(1996)

Article Doi