Examination of a Series of 8-propyl>-1-aryl-1,3,8-triazaspirodecan-4-ones as Potential Antipsychotic Agents

DOI: 10.1021/jm00150a011

Source and publish data:

Journal of Medicinal Chemistry p. 1811 - 1817 (1985)

Update date:2022-08-03

Topics:

Authors:

Wise, Lawrence D.

Pattison, Ian C.

Butler, Donald E.

DeWald, Horace A.

Lewis, Edward P.

et al. et al.

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Article abstract of DOI:10.1021/jm00150a011

8-<3-propyl>-1-phenyl-1,3,8-triazaspiro<4.5>decan-4-one (3) and related compounds have been shown to have antipsychotic profiles in biochemical and behavioral pharmacological test models.The dose of 3 necessary to produce catalep

Full text of DOI:10.1021/jm00150a011

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Product name:8-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

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