Examination of a Series of 8-propyl>-1-aryl-1,3,8-triazaspirodecan-4-ones as Potential Antipsychotic Agents

DOI: 10.1021/jm00150a011

Source and publish data:

Journal of Medicinal Chemistry p. 1811 - 1817 (1985)

Update date:2022-08-03

Topics:

Authors:

Wise, Lawrence D.

Pattison, Ian C.

Butler, Donald E.

DeWald, Horace A.

Lewis, Edward P.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00150a011

8-<3-propyl>-1-phenyl-1,3,8-triazaspiro<4.5>decan-4-one (3) and related compounds have been shown to have antipsychotic profiles in biochemical and behavioral pharmacological test models.The dose of 3 necessary to produce catalep

Full text of DOI:10.1021/jm00150a011

Products guided by the article

Product name:8-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

Cas No:97861-01-3

R&D Labs maybe for 97861-01-3

KindChem Co.,Ltd,

Contact:+86-25-85281586

Address:13F,Bld2#,South of Longpan Road
Wuhan Fortuna Chemical Co.,Ltd

website:http://www.fortunachem.com

Contact:86-27-59207850

Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
Shanghai Gsyn Chemical Co.,Ltd.

Contact:86-021-67158290

Address:86-021-67158291
Zhejiang Allied Chemical Co.,Ltd

Contact:18967038207

Address:Area A-30, High-tech Industrial Park, Quzhou, Zhejiang, China.

Relevant to this article

ANSA-STEROIDS

Doi:10.1016/S0040-4039(00)98316-3
(1985)
Physical-chemical studies and reactivity of new divalent germanium species

Doi:10.1016/s0020-1693(96)05294-2
(1996)
Synthesis of derivatives of (2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoic acid, a constituent of the didemnins

Doi:10.1039/P19960001427
(1996)
The Acrylamide Moiety as an Activated Alkene Component in the Intramolecular Baylis-Hillman Reaction: Facile Synthesis of Functionalized α-Methylene Lactam and Spirolactam Frameworks

Doi:10.1002/ejoc.201301526
(2014)
Doi:10.1021/jm00234a008
(1976)
Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

Doi:10.1016/S0040-4039(96)02083-7
(1996)

Article Doi