5-(Haloalkyl)-2'-deoxyuridines: A Novel Type of Potent Antiviral Nucleoside Analogue

DOI: 10.1021/jm00149a024

Source and publish data:

Journal of Medicinal Chemistry p. 1679 - 1684 (1985)

Update date:2022-08-04

Topics:

Authors:

Griengl, Herfried

Bodenteich, Michael

Hayden, Walter

Wanek, Erich

Streicher, Wolfgang

et al. et al.

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Article abstract of DOI:10.1021/jm00149a024

Syntheses of 5-(2-haloethyl)-2'-deoxyuridines, 5-(3-chloropropyl)-2'-deoxyuridines, and 5-(2-chloroethyl)-2'-deoxycytidine are described.The antiviral activities of these compounds were determined in cell culture against herpes simplex virus types 1 and 2

Full text of DOI:10.1021/jm00149a024

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