5-(Haloalkyl)-2'-deoxyuridines: A Novel Type of Potent Antiviral Nucleoside Analogue

DOI: 10.1021/jm00149a024

Source and publish data:

Journal of Medicinal Chemistry p. 1679 - 1684 (1985)

Update date:2022-08-04

Topics:

Authors:

Griengl, Herfried

Bodenteich, Michael

Hayden, Walter

Wanek, Erich

Streicher, Wolfgang

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00149a024

Syntheses of 5-(2-haloethyl)-2'-deoxyuridines, 5-(3-chloropropyl)-2'-deoxyuridines, and 5-(2-chloroethyl)-2'-deoxycytidine are described.The antiviral activities of these compounds were determined in cell culture against herpes simplex virus types 1 and 2

Full text of DOI:10.1021/jm00149a024

Products guided by the article

Product name:5-(2-Chloro-ethyl)-1-(5-chloromethyl-4-hydroxy-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione

Cas No:97975-02-5

R&D Labs maybe for 97975-02-5

Nanjing Chemlin Chemical Co., Ltd.

website:http://www.echemlin.cn

Contact:+86-25-83697070

Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Shenzhen Sunrising Industry Co., ltd.

Contact:+86 755 86571158 / 86571159 / 86571160

Address:2108 ZHENYE INT. BUSINESS CENTER,NO.3101-90 QIANHAI RD, NANSHAN,SHENZHEN, CHINA
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China
Deer Chemicals Co., Ltd.

Contact:+86-13666670345

Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China

Relevant to this article

Fischer indolization of ethyl pyruvate 2-[2- (trifluoromethyl)phenyl]phenylhydrazone and new insight into the mechanism of the Goldberg reaction. (Fischer indolization and its related compounds. XXVI)

Doi:10.1248/cpb.43.1281
(1995)
Regioselektive Reaktionen der fremdligandfreien Titanocen-Alkin-Komplexe Cp2Ti(RC2SiMe3)(R=Me3Si, Ph, t-Bu, n-Bu)

Doi:10.1016/0022-328X(95)98949-Z
(1995)
Fluorination of methyl 6-deoxy-1-thiohexopyranosides with diethylaminosulfur trifluoride (DAST), and the formation of unexpected products

Doi:10.1016/0008-6215(93)84076-I
(1993)
Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease

Doi:10.1021/jo00129a037
(1995)
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin

Doi:10.1021/acs.jmedchem.0c01809
(2021)
Convenient synthesis of N1-substituted orotic acid derivatives

Doi:10.1016/j.tetlet.2014.10.005
(2014)

Article Doi