A Synthesis of α-Substituted Amines

DOI: 10.1021/jo00220a040

Source and publish data:

Journal of Organic Chemistry p. 3885 - 3890 (1985)

Update date:2022-07-30

Topics:

Authors:

Hwang, Yuing C.

Chu, Min

Fowler, Frank W.

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Article abstract of DOI:10.1021/jo00220a040

The reaction of amides with organolithium reagents followed by hydride reducing agents has been studied as a synthetic route to α-substituted amines.The stereochemistry of the amine has been observed to depend upon the nature of the reducing agent.

Full text of DOI:10.1021/jo00220a040

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