Synthesis of Optically Active 2,3-Epoxycyclohexanone and the Determination of its Absolute Configuration

Article abstract of DOI:10.1021/jo01289a031

2,3-Epoxycyclohexanone (2a) has been obtained in optically active form by epoxidation of cyclohexenone in the presence of quininium benzyl chloride.The absolute configuration of the epoxy ketone has been established, and the transformation to (R)-(+)-cyclohex-2-en-1-ol (3) has been carried out without loss of optical activity.