Synthesis and Antiviral Activity of the Carbocyclic Analogues of 5-Ethyl-2'-deoxyuridine and of 5-Ethynyl-2'-deoxyuridine

DOI: 10.1021/jm00151a013

Source and publish data:

Journal of Medicinal Chemistry p. 79 - 84 (1986)

Update date:2022-08-04

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Authors:

Shealy, Y. Fulmer

O'Dell, C. Allen

Arnett, Gussie

Shannon, William M.

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Article abstract of DOI:10.1021/jm00151a013

The carbocyclic analogue of the antiviral agent 5-ethyl-2'-deoxyuridine (EDU) was synthesized by two routes.The pivotal step in the first route is the reaction of lithium dimethylcuprate with the carbocyclic analogue of 5-(bromomethyl)-2'-deoxyuridine dib

Full text of DOI:10.1021/jm00151a013

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