Nucleosides. 136. Synthesis and antiviral effects of several 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-alkyluracils. Some structure-activity relationships

DOI: 10.1021/jm00151a025

Source and publish data:

Journal of Medicinal Chemistry p. 151 - 154 (1986)

Update date:2022-08-04

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Authors:

Watanabe

Schinazi

Fox Fox

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Article abstract of DOI:10.1021/jm00151a025

In order to study structure-activity relationships between antiherpetic activity and the size of the C-5 alkyl substituents of 2'-fluoro-ara-U derivatives, six new nucleosides (1c-h) were synthesized. The 5-allyl analogue 1c was prepared by a Pd(II)-catal

Full text of DOI:10.1021/jm00151a025

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