TOTAL SYNTHESIS OF (+/-)-PODOPHYLLOTOXIN AND (+/-)-EPIPODOPHYLLOTOXIN

DOI: 10.1016/S0040-4020(01)87656-0

Source and publish data:

Tetrahedron p. 4297 - 4308 (1986)

Update date:2022-08-03

Topics:

Authors:

Eyken, J. Van der

Clercq, P. de

Vandewalle, M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)87656-0

A novel approach to (+/-)-epipodophyllotoxin (2c) and hence also to (+/-)-podophyllotoxin (1c) is described, involving as a key-step the stereoselective ring closure of the TMS-ester derived from 17a to the tetralin derivative 30c with mesyl chloride.

Full text of DOI:10.1016/S0040-4020(01)87656-0

Products guided by the article

Product name:(4aS,5S,6S,11bR)-2,2-Di-tert-butyl-6-(3,4,5-trimethoxy-phenyl)-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-2-sila-cyclopenta[b]phenanthrene-5-carboxylic acid

Cas No:99463-57-7

R&D Labs maybe for 99463-57-7

Henan Yellow River New Material Technology Co.Ltd.

website:http://www.yellowriverchem.com

Contact:0086-373-7278760

Address:Chengguan Town, Yuanyang County
SINFACHEM LIMITED

Contact:86-25-84683399

Address:605, Phoenix Herui Plaza, No.389, South Taiping Road, Nanjing, China 210002
KindChem Co.,Ltd,

Contact:+86-25-85281586

Address:13F,Bld2#,South of Longpan Road
Weihao Chemtech (ChangZhou) Co., Ltd.(expird)

Contact:051989185693

Address:NO 217 huangshan Rd ,Changzhou
STAR SYNTHESIS CO.,LIMITED

Contact:+(852) 301-98033

Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong

Relevant to this article

Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols

Doi:10.1016/S0040-4039(98)01988-1
(1998)
(1-Phenyl-1H-1,2,3,4-tetrazole-5-thiolato-S)-bis(triphenylphosphine) silver(I) methanol solvate

Doi:10.1107/S0108270199000311
(1999)
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

Doi:10.1038/s41467-017-00833-9
(2017)
Sensitized photoxidation of compounds apparently from carotenoids

Doi:10.1111/j.1751-1097.1969.tb05911.x
(1969)
Carbonate, acetate and phenolate phosphonium salts as catalysts in transesterification reactions for the synthesis of non-symmetric dialkyl carbonates

Doi:10.1039/c2ob25447f
(2012)
Preparation and investigation of Ce(III). Th(IV) and U(VI) chelates with some Schiff bases derived from 5.7-dihydroxy-6-formyl-2-methylbenzopyran-4-one

Doi:10.1080/00945719909349495
(1999)

Article Doi