Tetrahedron p. 4297 - 4308 (1986)
Update date:2022-08-03
Topics:
Eyken, J. Van der
Clercq, P. de
Vandewalle, M.
A novel approach to (+/-)-epipodophyllotoxin (2c) and hence also to (+/-)-podophyllotoxin (1c) is described, involving as a key-step the stereoselective ring closure of the TMS-ester derived from 17a to the tetralin derivative 30c with mesyl chloride.
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