Tetrahedron p. 2837 - 2841 (1982)
Update date:2022-08-05
Topics:
Korhonen, Ilpo O. O.
Pitkaenen, Maija
Korvola, Jorma N. J.
The additions of chlorine, bromine and bromine chloride to trans methyl 2-butenoate 1, trans methyl 2-methyl-2-butenoate 2 and methyl 3-methyl-2-butenoate 3 under ionic conditions were studied.Bromine chloride addition always gave as a major regioisomer the 2-bromo-3-chloro compound, almost quantitatively in the case of 3.The mechanism of bromonium ion ring-opening (SN1 or SN2) is discussed with respect to the double bond substitution and regioisomer proportions.The dihalo products were identified by MS, 1H and 13C NMR.
View MoreContact:+86-371-86058576
Address:NO.32, Jingsan Road, Zhengzhou, China
Contact:+86-25-85281586
Address:13F,Bld2#,South of Longpan Road
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.
Contact:+86-25-83767696
Address:14-7 Zhongshan Lu Guluo District, Nanjing
Contact:86-532-68629711 13780605697
Address:NO 220 YANAN 3 ROAD,(POST ADMINISTRATION BUILDING),QINGDAO,CHINA
Contact:+86-531-58668191 58668193 58668196 58661173
Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
Doi:10.1016/S0040-4020(01)96560-3
(1985)Doi:10.1246/cl.1985.1127
(1985)Doi:10.1002/jhet.5570220303
(1985)Doi:10.1021/jo00355a021
(1986)Doi:10.1002/poc.752
(2004)Doi:10.1016/j.bmcl.2007.11.122
(2008)
