STUDIES OF HETEROCYCLIC COMPOUNDS. 8. THE SYNTHESIS AND SOME REACTIONS OF 4-BROMOIMIDAZOLE-5-SULFONYL DERIVATIVES.

Article abstract of DOI:10.1021/je00044a036

The chloride, azide, and amides of 4-bromoimidazole-5-sulfonic acid were prepared by the reaction of the sulfonic acid with phosphorus pentachloride and the treatment of the resulting imidazolesulfonyl chloride with sodium azide and various aromatic and heteroaromatic amines. The sulfonyl azide was further reacted with trisubstituted phosphines, norbornene, indole, and N-methylindole to give new compounds of expected biological activity. The infrared and mass spectra of some of the compounds are presented.