Catalytic Friedel-Crafts Acylation Reactions Using Hafnium Triflate as a Catalyst in Lithium Perchlorate-Nitromethane

Article abstract of DOI:10.1016/0040-4039(94)02221-V

Catalytic Friedel-Crafts acylation reactions were performed by using hafnium trifluoromethanesulfonate (hafnium triflate, Hf(OTf)4) as a catalyst.The catalytic activity of the Lewis acid catalyst was much improved in lithium perchlorate-nitromethane (LiClO4-MeNO2) and the yield was up to 250,000percent based on the catalyst.Various substituted benzenes reacted with acid annhydrides in the presence of a catalytic amount of Hf(OTf)4 to give the corresponding aromatic ketones in high yields.