Palladium-catalyzed synthesis of aromatic acids from carbon monoxide and aromatic compounds via the aromatic C-H bond activation

Article abstract of DOI:10.1016/0022-328X(90)87292-L

Various aromatic acids can be prepared from aromatic compounds and CO under mild conditions by Pd-based catalysts via direct aromatic C-H bond activation.With Pd^II catalysts, the reaction is electrophilic and proceeds with ortho-para orientation when an electron-donating group is attached to the benzene ring; addition of t-BuOOH and allyl halides makes the reaction catalytic with respect to palladium(II). β Naphthoic acid can be prepared from naphthalene and CO by the Pd/phenanthroline catalyst system in 421percent yield based on Pd and in 92percent selectivity.