Tetrahedron Letters p. 6077 - 6078 (1999)
Update date:2022-08-11
Topics:
Zabjek, Alenka
Petric, Andrej
An efficient method is described for the cleavage of enolisable aryl methyl and aryl ethyl ketones using an excess of KOH in DMF at an elevated temperature. It presents a general hydrolytic method yielding aromatic carboxylic acids, and is complementary to the widely used oxidative methods for ketone cleavage.
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