Tin(II) chloride dihydrate: A mild and efficient reagent for cleaving acetals

Article abstract of DOI:10.1016/S0040-4039(00)91878-1

Tin(II) chloride dihydrate (SnCl₂·2H₂O) efficiently converts conjugated dioxolones, and both dimethoxy and diethoxy acetals to aldehydes (84-98%). Similarly, nonconjugated dimethoxy and diethoxy acetals are also efficiently converted to aldehydes (84-94%). Conjugated pyrans and nonconjugated dioxolanes, however, are only converted to aldehydes in 17-38% yields.