Asymmetric synthesis XXII: Asymmetric catalytic trimethylsilylcyanation of benzaldehyde by novel Ti(IV)-chiral Schiff base complexes

Article abstract of DOI:10.1016/0957-4166(95)00025-K

Benzaldehyde has been trimethylsilylcyanated with a catalyst prepared in situ from titanium tetraisopropoxide and a novel chiral Schiff base. Both (R) and (S) cyanohydrins are obtained in moderate e.e. values.