Chemical and Pharmaceutical Bulletin p. 1186 - 1188 (1998)
Update date:2022-08-16
Topics:
Yoshikawa, Masayuki
Murakami, Toshiyuki
Morikawa, Toshio
Matsuda, Hisashi
New carabrane-type sesquiterpenes, curcarabranols A and B, were isolated from zedoary together with the two known carabrane-type sesquiterpenes curcumenone and 4S-dihydrocurcumenone. The absolute stereostructures of these carabrane-type sesquiterpenes were determined on the basis of physicochemical and chemical evidence. Zedoary sesquiterpenes including 4S-dihydrocurcumenone and curcarabranols A and B were found to inhibit the contraction induced by a high concentration of K+ in isolated rat aortic strips.
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