Journal of the American Chemical Society
Communication
(22) Mishra, R.; Sjolander, D.; Hammarstrom, P. Mol. BioSyst. 2011,
̈
̈
Notes
7, 1232−1240.
The authors declare no competing financial interest.
(23) Brandenburg, E.; Berlepsch, H.; Koksch, B. Mol. BioSyst. 2012,
8, 557−564.
ACKNOWLEDGMENTS
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(24) Benzeid, H.; Mothes, E.; Essassi, E. M.; Faller, P.; Pratviel, G.
C.R. Chimie 2012, 15, 79−85.
Financial support from the NIH [CA 133002 (E.A.T.) and
R01NS069566 (C.S.)] is gratefully acknowledged. We also
thank the NSF for financial support [CHE-9709183, CHE-
0741968, and CHE-0847530 (J.Y.)]. We thank Dr. Christina C.
Capule for help with the binding studies. We also thank Dr.
Edward Koo for the brain samples from AD transgenic mice.
(25) Nilsson, K. P. R. FEBS Lett. 2009, 583, 2593−2599.
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(28) Nile red has previously been reported to emit fluorescence at
different wavelengths upon binding to a few different amyloid fibrils in
solution. Nile red was not, however, capable of discriminating Aβ
versus prion fibrils. Additionally, Nile red is not suitable for histological
studies due to its poor selectivity for binding to amyloid plaques
compared to other biologics present in tissue. See ref 22.
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NOTE ADDED AFTER ASAP PUBLICATION
A typographical error in the title was corrected October 9,
2012.
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