A NEW SOURCE FOR GENERATION OF BENZYNE AND PYRIDYNE: REACTIONS OF O-HALOPHENYL (OR 3-BROMO-4-PYRIDYL) PHENYL SULFOXIDES WITH GRIGNARD REAGENTS

Article abstract of DOI:10.1016/S0040-4039(00)96192-6

o-Chloro- and o-bromophenyl phenyl sulfoxides and (3-bromo-4-pyridyl) phenyl sulfoxide were treated with Grignard reagents to generate benzyne (or 3,4-pyridyne) in THF.The o-iodophenyl derivative, on the other hand, gave mainly o-(arylsulfinyl)phenyl Grignard reagent.