Selectivity in palladium(0)-catalyzed cross-coupling reactions: Application to a tandem Stille reaction

Article abstract of DOI:10.1016/0040-4039(95)01985-Q

A tandem palladium-catalyzed cross-coupling reaction between a pyridyl triflate 1a and a variety of aryl bromides mediated by hexamethylditin is described. The reaction apparently proceeds via the intermediacy of the labile pyridylstannane 1b indicating that the oxidative addition of palladium(0) to the triflate, subsequent transmetalation with hexamethylditin and reductive elimination occurs selectively in the presence of the aryl halide.