Paper
Green Chemistry
After waiting for the reactor to reach steady state (∼3 residence
times), a sample vial was placed at the outlet and the product
was collected for ∼2 residence times. The sample was worked
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Acknowledgements
We thank the Novartis-MIT Center for Continuous Manufactu-
ring for support of this work. S. G. N. thanks the Natural 13 For recent overviews, see: (a) J.-i. Yoshida, in Flash Chem-
Sciences and Engineering Research Council of Canada (NSERC)
for financial support in the form of a postdoctoral fellowship.
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DOI: 10.1021/op400120g.
180 | Green Chem., 2014, 16, 176–180
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