Enantioselective synthesis of (S)-1-methyldodecyl acetate, a pheromone of Drosophila mulleri, via (-)-sparteine-assisted deprotonation of 1-dodecanol

Article abstract of DOI:10.1055/s-1992-26340

The title compound was synthesized with 98% ee by enantioselective lithiation and methylation of 1-dodecanol, employing a new protection/activation method for primary alcohols, followed by asymmetric deprotonation of the carbamate.