Studies of Regio- and Stereoselectivity in Some Nucleophilic Ring Opening Reactions of N-Tosyl-3-phenyl-2-aziridinemethanols and Derivatives

Article abstract of DOI:10.1016/0040-4020(95)00429-C

A study has been made of the regio- and stereoselectivity of the ring opening reactions of the 3-aryl substituted aziridines 1 and 2.The regiochemical outcome is apparently decided by a balance of electronic activation at C-3 by the phenyl group and the c